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55,268 High glucose levels impair mitochondrial oxidative phosphorylation, decreasing ATP production and increasing ROS generation

and the Deutsche Diabetes Gesellschaft 58th Jahrestagung, 811 May 2024 in Berlin, Germany

Notably, an ongoing RCT investigating the effects of semaglutide on pre-treatment cognitive dysfunction in patients with major depression may provide useful insights in this regard (NCT04466345 (ref