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(4) mGPDH in the regulation of ferroptosis G3P metabolism supports ferroptosis defense in disease contexts In the first study identifying mGPDH as a ferroptosis regulator, metabolomic analyses revealed that treatment of cancer cells with GPX4 inhibitors led to a marked depletion of intracellular glycerol3phosphate (G3P) 99

( D ) Human Fc fragment was coated onto an ELISA plate and incubated with titrated amounts of purified gp34 1-179 , gp34 1-179W65F or ICOS-L 1-268