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Research Applications of Semaglutide GLP-1 receptor pharmacology in pancreatic beta-cell models and HEK293 cells expressing the human GLP-1R, where semaglutide is the standard long-acting agonist used to characterize receptor binding affinity, EC values, and downstream cAMP signalling

These drugs work by mimicking a hormone the body produces naturally, one that slows digestion, stimulates insulin production, and signals the brain to reduce appetite

J Arthroplasty 40, 30893096.e3081 (2025)

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