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Geographical Distribution: Higher rates are seen in regions with temperate climates where fluctuations in the temperatures are common

This peptide has a more established research base and safety profile when used appropriately

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In recent years, the therapeutic footprint of this class has grown: long-acting agents (e.g., liraglutide, semaglutide) and next-generation dual/triple agonists (e.g., tirzepatide) have demonstrated superior glycemic control, weight reduction, and cardiovascular benefits in adults with T2DM (Yao et al., 2024)