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Gonadotrophins inhibit the expression of insulin-like growth factor binding protein-related protein-2 mRNA in cultured human granulosa-luteal cells

R Dicoumarol (a competitive inhibitor of NQO1 at the NADPH binding site) blocks this p53 stabilization, confirming that NQO1 catalytic activity is required for the protective effect

REFERENCES Abenavoli, L

The identified metabolites included amino acids and derivatives, fatty acids, lipid mediators, excretion metabolites, bile acids, organic acid and purine/pyrimidine metabolites

Healthy microbiota produces short-chain fatty acids (SCFAs) like butyrate for anti-inflammatory effects