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doi:10.1200/JCO.2002.10.018

Mandrika and colleagues (Biochem Pharmacol, 2001, PMID 11239505) examined melanocortin peptides on NF-B DNA binding in RAW 264.7 macrophage-like cells and reported evidence for dual mechanisms of action, and Kannengiesser and colleagues (Inflamm Bowel Dis, 2008, PMID 18092346) reported effects in murine colitis models that were partly independent of MC1R

Peptides such as GHK-Cu and zinc thymulin are widely used in topical formulas to support scalp conditions associated with healthy-looking hair

Jacqueline Maya, M.D., from Massachusetts General Hospital-Mass General Brigham in Boston, and colleagues conducted a retrospective cohort study of 149,790 singleton pregnancies delivered between June 1, 2016, and March 31, 2025, to compare weight gain and pregnancy outcomes with and without exposure to GLP-1 RAs before or during early pregnancy