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Age-related cohesion loss around centromeres, a significant contributor to errors in chromosome segregation, is exacerbated by ROS-induced oxidation and carbonylation of proteins essential for spindle formation and stability, thereby increasing the risk of aneuploidy in offspring [4, 38]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Helton E, Darragh R, Francis P, et al