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Other factors like body fat percentage can offer more context

A.Mun-BryceS.WesleyM.KornfeldM

When calorie deficit persists over weeks and months, the body increasingly mobilizes visceral fat deposits for energy

As a result, coverage of GLP-1 drugs for the treatment of obesity remains optional for states, while coverage is required for drugs approved for the treatment of diabetes and, since March 2024 and December 2024, for the treatment of cardiovascular disease (Wegovy) and moderate to severe obstructive sleep apnea in adults with obesity (Zepbound), respectively (Table 1)

Kuraoka S, Oda M, Ohba T, Mitsubuchi H, Iwai-Shimada M, Tatsuta N, Kamijima M, Nakamura K, Katoh T (2024) Association between prenatal mercury exposure and pediatric neurodevelopment: the Japan Environment and Childrens Study