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Nature 450:712716 Chakrabarti P, English T, Karki S et al (2011) SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL
The other activates GLP-1 receptors that seem to influence dopamine signaling more broadly
The research team found that participants with genetic makeup mimicking the effect of GLP-1 receptor agonists leads to reductions in both lean mass (whole-body fat-free mass and trunk fat-free mass) and body fat (whole-body fat mass, trunk fat percentage and body fat percentage)
2010;299(6):C148592
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