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GLP-1 agonists, Cleveland Clinic (2023) Nutritional modulation of endogenous glucagon-like peptide-1 secretion: A review , Nutrition & Metabolism (2016) Closing Americas fiber intake gap, American Journal of Lifestyle Medicine (2016) Easy ways to boost fiber in your daily diet, Academy of Nutrition and Dietetics (2021) The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon, The American Journal of Physiology-Gastrointestinal and Liver Physiology (2018) Mediterranean diet effects on Type 2 diabetes prevention, disease progression, and related mechanisms

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Mechanism Behind GLP-1 RAs Kidney Protection A unique aspect of GLP-1 receptor agonists lies in their ability to reduce oxidative stress, a process that, when unchecked, can accelerate kidney damage in diabetic patients

However, the hyperglycemic effects of glucagon pose a challenge for its therapeutic application [77]

Semaglutide, in particular, has demonstrated a reduction in major cardiovascular events in clinical trials