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95% male) who received care in fiscal years 2017 to 2023, 12% received at least one prescription for a GLP-1 RA, most commonly dulaglutide, semaglutide, or tirzepatide (which is also an agonist of the glucose-dependent insulinotropic polypeptide [GIP] receptor)
Hunt ND, Li GD, Zhu M, et al
Ozempic (semaglutide) is a GLP-1 receptor agonist used for type 2 diabetes management, administered as a once-weekly subcutaneous injection
Personalized Gut Health Insights Through Genetic Testing The PlexusDx Precision Peptide Genetic Test ($99 add-on after your first month) analyzes GLP1R variants that relate to GLP-1 and related signaling pathways
Relevant mechanisms involve iron metabolism disruption, oxidative stress, intestinal barrier damage, and immune microenvironment imbalance
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