The exact duration depends on factors like your individual metabolism, overall health, and how severe any vitamin deficiencies are to begin with
Apoptosis was determined using Caspase Glo 3/7 (Promega)
However, when combined with semaglutide, which reduces appetite and calorie intake, it can sometimes lead to dehydration
While early cross-sectional studies yielded inconsistent results regarding this association [5557], more robust prospective longitudinal cohort studies have provided compelling evidence

Niya Mansuri, weight loss expert at myBMI Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen (2026) EMC [accessed 9 March 2026] Ozempic 0.25 mg solution for injection in pre-filled pen (2025) EMC [accessed 9 March 2026] Non-alcoholic fatty liver disease (NAFLD) (2025) NHS [accessed 9 March 2026] Sleep apnoea (2022) NHS [accessed 9 March 2026] Physical activity guidelines for adults aged 19 to 64 (2024) NHS [accessed 9 March 2026] Semaglutide for managing overweight and obesity (2023) NICE [accessed 9 March 2026] Tirzepatide for managing overweight and obesity (2025) NICE [accessed 9 March 2026] Once-weekly semaglutide 72 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial (2025) National Library of Medicine [accessed 9 March 2026] Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension (2022) National Library of Medicine [accessed 9 March 2026] Wegovy (2025) Novo Nordisk [accessed 9 March 2026] Its natural to have questions, and were here to keep things straightforward so you can stay focused on your journey
