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Of course, if youre depressed, Miller emphasizes, you shouldnt self-medicate with any supplement, B12 included

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He identified a cascade from oral microbiome disruption to systemic inflammation and gut permeability

The most responsible framing is: Short-term tolerability is not the same as long-term safety Manufacturing quality heavily affects risk People with medical conditions or those taking medications should talk to a clinician before considering unapproved substances

A clinical trial involving 120 people with gut Candida and digestive symptoms found that what they ate may have significantly improved treatment results