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Gastroenterology 132 , 21312157, doi:10.1053/j.gastro.2007.03.054 (2007)

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Nat Rev Gastroenterol Hepatol 10:33044

Individual academic studies cannot serve as the primary evidence for drug approval

Titration is slow and intentional, which is exactly what reduces the side effects people worry about including muscle loss and the facial volume changes sometimes called Ozempic face. A doctor who manages your pace, monitors your protein intake, and recommends resistance training makes a real difference