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Despite unpredictable in most cases, the occurrence of AKI is significantly higher in severe I/R injury after kidney transplant surgery, cisplatin for tumor chemotherapy, or contrast media for radiography and so on, especially for the susceptible individuals, including old age and patients with diabetes mellitus or CKD (Zhang et al., 2020)

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Conversely, NRF2 activators like SFN, RSV, and curcumin enhance NRF2-mediated antioxidant defenses, offering cytoprotection in degenerative and inflammatory conditions

5-Amino-1MQ is a laboratory research material used to study NNMT-related metabolic pathways, nicotinamide handling, NAD+ homeostasis, and cellular energy regulation in controlled experimental systems