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These commenters stated that screening for SDOH is fundamental to patient-centered care, including clinical outcomes, treatment adherence, and reducing preventable healthcare utilization (for example, emergency department visits and readmissions)

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The ILK/PI3K/Akt survival signalling activated by TB-500 is also relevant to neuronal survival following ischaemic and traumatic CNS injury , providing an anti-apoptotic neuroprotective mechanism alongside the pro-migratory effects on neural repair cell populations