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The said petition must be accompanied by a copy of the validly issued CPR, clear and comprehensive photographic evidence of the compliant supplement in its final commercial presentation, and a copy of the subject FDA Advisory for official verification and validation

& Hylemon, P

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5a and c), implying that T1 may function as a copper chelator to abolish the tyrosinase activity and this can be evident by our inhibition assay result T1 is a strong competitive inhibitor of mushroom tyrosinase (Supplementary Fig