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Semaglutide, tirzepatide, and the investigational triple agonist retatrut Orforglipron (developmental code LY3502970, brand name Foundayo) is the first orally administered, small-molecule glucagon-like peptide-1 (GLP-1) receptor agonist to reach late-st The question of how Melanotan II modulates melanocortin 1 receptor (MC1R) signaling sits at the intersection of receptor pharmacology and pigment biology