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In a case-control study in 23 adolescents with PCOS and 21 healthy controls, myo-inositol plus lipoic acid treatment for six months was studied

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These alterations are associated with notable enhancements in renal function parameters, including reductions in serum creatinine (25%) and blood urea nitrogen (18%) (86, 87)

Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K (2004) Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis