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Figure 2 Within the central nervous system, GLP-1RAs function to reduce hunger sensations, suppress appetite, lower caloric intake, amplify satiety, and facilitate better management of eating behaviors (98102)

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In the CNS, GLP-1Rs are expressed by neurons in the hippocampus, which is known to be a cognition-related brain region, and have been observed in neocortical pyramidal neurons (Hamilton and Holscher, 2009)

The EPIC Study's authors' footnote for that choice cites a November 2002 report of another study of solely cavaliers, in this case 166 of them

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