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doi: 10.1186/s12967-022-03296-9

[3] [4] Clinical trials have demonstrated substantial reductions in hemoglobin A1c (up to 2.5% reduction from baseline) and body weight (up to 20% reduction from baseline) in the SURPASS and SURMOUNT clinical trial programs

They share the same receptor mechanism yet differ in cadence and clinical history

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OGD/R, oxygen-glucose deprivation/reperfusion