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The researchers assessed kidney oxygenation (R2*) using blood oxygenation leveldependent MRI, and they assessed mean global kidney perfusion (GKP), renal artery resistive index (RARI), and cortical and medullary estimates of fibrosis (diffusion-weighted imaging for the apparent diffusion coefficient [ADC]) with phase-contrast MRI-measured arterial flow

Lipid peroxidation including the generation of reactive oxygen species (ROS), transforming growth factor-, and tumor necrosis factor- can be implicated as a cause of hepatic fibrosis