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Paul Edison, a professor of neuroscience at Imperial College London who worked with Novo Nordisk on an earlier Alzheimers trial, said the participants in the trials may have been treated too late in their disease

Hong, H., Chen, L., Zhong, Y., Yang, Z., Li, W., Song, C., & Leng, H

It was recently suggested that 24 weeks of therapy might be sufficient for patients with a baseline viral load below 600,000 IU/ml in whom pegylated IFN alfa-2b-based treatment yields a 2-log decline at week 12 and undetectable HCV RNA at week 24 [24 ]

In rodent models, peripheral administration of exendin-4 (EX4), a GLP-1RA has been shown to reduce motivation for sucrose, as evidenced by decreased responding in progressive ratio operant-conditioning tasks (Dickson et al., 2012)

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