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Millions of people have used it since FDA approval, and the side effect profile is well-characterized

However, some research has shown that up to 500 mcg had positive effects on homocysteine levels in the bodywhen combined with .5-5 mg of folic acid

GLP-1RA Reward Behaviour Systematic Review (PubMed, 2024) GLP-1 Receptor Signalling in Reward Circuitry, Dopamine, and Addiction Research A systematic review of GLP-1 receptor agonist effects on reward behaviour published on PubMed following PRISMA guidelines across OVID, PubMed, Scopus, and Google Scholar evaluated the evidence for GLP-1Rs role in reward dysfunction across obesity, type 2 diabetes, and psychiatric conditions

It is studied for its potential to support tissue regeneration, angiogenesis, and cellular signaling in tendon, ligament, muscle, and gut models

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