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Also because of the lack of Fc compared to standard mAbs (i.e

M., Vieira, L

Comparison with Other Therapies Phase 1 trials demonstrated that Retatrutides safety profile was comparable to other GLP-1 receptor agonists, with no unexpected safety signals identified

En abril de 2024, el fabricante anunci mediante comunicado de prensa que SURPASS-CVOT haba alcanzado su objetivo primario, mostrando que tirzepatida no aumentaba el riesgo cardiovascular (no inferioridad) y sugiriendo posibles beneficios