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Concomitant with Wnt ligand production, placode epithelial cells also express the Wnt inhibitor Dkk (Bazzi et al., 2007)

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Medical Conditions Requiring Caution: Individuals with heart conditions Those with liver or kidney disease People with metabolic disorders Patients with Leber's disease (affecting the optic nerve) Those with low potassium levels (hypokalemia) [12] Pregnancy and breastfeeding present special considerations for MIC B12 treatment