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When NAD+ levels drop, mitochondrial function suffers, energy production declines, and metabolism slows

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Increased mucin secretion, particularly MUC5AC, is associated with asthma, and the mucus plugs generated by the asthmatic airway are hypothesized to be generated by eosinophil peroxidase crosslinking of mucus thiol groups to stiffen the mucus gels and prevent clearance (Dunican et al., 2018a)

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