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In adults, major chronic diseases [13], including cardiovascular and renal disease, and neurological decline, are also strongly associated with toxic elements

doi: 10.1016/S0735-1097(99)00553-7

Special considerations : The FDA prescribing information for tirzepatide notes that it may decrease exposure to oral contraceptives, particularly during dose initiation and escalation

That is where patients may run into issues, like the pre-op patient who did not report the compounded semaglutide on their H&P for their surgery because they didnt realize it was a medication

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