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doi: 10.1056/NEJMoa1812389 9 MosenzonOWiviottSDCahnARozenbergAYanuvIGoodrichELet al

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The risk-benefit profile of triple agonists remains under investigation

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This phenomenon is further illustrated by results from a randomized, open-label mechanistic trial in patients with T2DM, which demonstrated that lixisenatide, with a half-life of 2 4 hours, had a significantly greater effect than liraglutide in delaying in gastric emptying and curtailing postprandial glucose excursions following a standardized solid breakfast (156)

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