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How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test identifies predispositions in GLP-1 receptor sensitivity (GLP1R rs6923761), appetite regulation (FTO rs9939609, MC4R rs17782313), and glucose-incretin pathways

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GIP, or glucose-dependent insulinotropic polypeptide, is another incretin hormone with overlapping but distinct effects on insulin secretion, appetite and metabolism

The results for combined agonism in mice and rats are promising with improved glucose tolerance but also greater reductions in body weight and fat with the dual agonists compared to GLP-1r agonism alone (38, 183)

Instead, it is used as a part of a more comprehensive hormone replacement therapy plan