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[2] [3] It is also often observed in thumb-sucking children with primary HSV-1 oral infection (autoinoculation) prior to seroconversion, [1] and in adults aged 20 to 30 following contact with HSV-2-infected genitals

Type I collagen provides tensile strength and structure, while Type III collagen offers flexibility and support to blood vessels and organs

Cirrhosis also leads to pigmentation changes, with 46.9% of patients experiencing blotchy or diffuse muddy gray hyperpigmentation

Target: mid-range for age and sex, not above upper limit