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You also assess how you feel and adjust the dose if needed

When your body loses fluids through sweating, illness, exercise, or simply not drinking enough water, your blood volume decreases slightly

Kruse, Thomas

Cost NMN supplements are typically taken every day, and can be pricey, so you may want to consider your budget before purchasing

The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases