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AE adverse event, ALK anaplastic lymphoma kinase, ALT alanine aminotransferase, AST aspartate aminotransferase, c-MET hepatocyte growth factor receptor, CRPC castration-resistant prostate cancer, CX cisplatin and capecitabine, ECX epirubicin, cisplatin and capecitabine, EGFR epidermal growth factor receptor, FOLFOX 5-fluorouraciI, folinic acid and oxaliplatin, GC gastric cancer, GEJ gastroesophageal junction cancer, HCC hepatocellular carcinoma, IV intravenously, NSCLC non-small cell lung cancer, TKI tyrosine kinase inhibitor 10

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doi: 10.1001/jama.2021.1831 84 WildingJPHBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al