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Alternatively, others like dulaglutide (Trulicity) are administered once a week

Press release - Intarcia announces successful cardiovascular safety results in phase 3 FREEDOM-CVO Trial for ITCA 650, an investigational therapy for type 2 diabetes

Starting at a smaller dose allows the body to acclimate to the medication before the dosage is stepped up over time

In people with T2D, 48% of the participants achieved 10% WL after 26 weeks of treatment with orforglipron 45 mg in a phase 2 trial (Fig

increasing dose over time as your body adjusts), side effects generally start off mild and get worse in the short-term as the dose increases