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Introduction Despite the advancement of knowledge on the pathophysiology of the carnitine palmitoyltransferase II (CPTII) deficiency, the clinical approach to nutrition and exercise in patients affected by this condition has remained unchanged since its beginning

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The main downside is that injections require more care

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At present, even though the comparative efficacy of tirzepatide vs these higher dosing regimens of dulaglutide and semaglutide is unknown, available data suggest that tirzepatide could be a reasonable treatment option when glycaemic control and body weight loss are therapeutic priorities