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And in a 2022 study of people with treatment-resistant bipolar depression, participants depression and functioning improved upon the reversal of insulin resistancea metabolic condition that is more common in people with bipolar disorder (J

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Malhotra continues

Certain atypical antipsychotics as adjunctive treatment in MDD, such as olanzapine and quetiapine, are also associated with metabolic adverse effects and drug-induced weight gain [150, 151]

NAD+ is essential in metabolic function, promoting athletic function, boosting brain repair, and function