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There was a tendency toward higher t 1/2 with increasing hepatic impairment, but applying the same rationale as stated above for participants with renal impairment, this was not considered clinically relevant

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Hydroxocobalamin (5-20 g) was administered to 14 consecutive patients beginning a median 2.1 hours after cyanide ingestion or inhalation

Using a tree shrew model, we also observed a significantly increased level of 8-OHdG in all HCV-infected tree shrews compared to that in control tree shrews 56