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62-65% of pregnant women use acetaminophen during pregnancy By 9 months of age: Up to 95% of children have been exposed to acetaminophen NEURODEVELOPMENTAL DISORDER PREVALENCE TIMELINE[] 1960s: Prevalence estimated at 1 in 10,000 1980s: Prevalence rises to 1 in 2,000 Late 1980s-1990s: Rates begin dramatic increase Late 1990s: Prevalence reaches 1 in 200 1996-2010: 269% increase in ASD prevalence (Atlanta surveillance data) 2021: Prevalence reaches 1 in 44 in the United States 1998-2018: 787% increase in recorded incidence in the UK THE TEMPORAL PATTERN The dramatic rise began in the late 1980s and accelerated through the 1990s and 2000sapproximately 25-30 years after acetaminophens introduction and widespread adoption in pregnancy, and coinciding with increased use for post-vaccination symptom management in infants

AEs leading to trial product discontinuation occurred in 6/90 (7%) participants in the CagriSema 2.4 mg/2.4 mg group, 11/93 (12%) participants in the CagriSema 1 mg/1 mg group, and 1/91 (1%) in the placebo group

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It is given as an injection by a doctor or nurse and should not be self-administered.

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