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GLP-1 medications like Ozempic, Mounjaro and Wegovy are already part of the mainstream in the US

230,231 By modulating the activity of K-ATP channels, GLP-1 indirectly controls the calcium signaling in -cells, thereby influencing glucagon secretion

Combination of GLP-1 and GIP: Approved as Mounjaro for type 2 diabetes and Zepbound for weight loss

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The most common adverse events were gastrointestinal symptoms such as nausea, vomiting, and diarrhea, which were generally mild to moderate