Dosage: Loading phase of 2-2.5 mg twice per week for 4-6 weeks, then maintenance at 2 mg/week
K562 cells were elected to be as a representative to analyze the intracellular GSH levels
Untreated tissues in 2% FBS DMEM were used as negative controls
The results of another randomized trial in 39 patients with Alzheimers disease suggested that supplementation with fish oil concentrate (high in omega-3 fatty acids) with or without lipoic acid (600 mg/day) for one year could delay the progression in cognitive and functional impairments assessed by the Instrumental Activities of Daily Living (IADL) scoring system compared to placebo (104)
In Arabidopsis, there are four OAS-TL isoforms: OAS A1, A2, B, and C (Yoshida et al., 2013), OAS C as a target of GRX (Rouhier et al., 2005), while OAS A1, OAS B, and OAS C have been reported as being persulfidated (Figure 2 and Supplementary Table 2