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Hsp70 Reduces alph-synuclein aggregation and Toxicity

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Besides, nicotine failed to improve other indications of obesity, including liver index (Figure 2C) and liver steatosis (Supplementary Figures 3E), fat accumulation (Figures 2D, E and Supplementary Figures 3F, G) and adipocyte enlargement (Figures 2FI)

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By contrast, peptides such as PYY and apelin were discontinued primarily due to formulation limitations or tolerability at supraphysiologic dosespharmacologic rather than biological failuresand therefore meet criteria for re-evaluation