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An open-label dose-escalation trial found administering another antioxidant and cofactor in the ETC, coenzyme Q10 (CoQ10

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Results Fragment-based drug design and chemistry Utilizing actives identified in a quantitative high-throughput screen against Schistosoma mansoni TGR 20,35 , 92 commercially available low molecular weight (MW) compounds/fragments were tested by X-ray crystallography 33,34,36