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The efficacy of bempedoic acid has been investigated in numerous phase II studies and 4 pivotal phase III studies in the CLEAR programme ( Cholesterol Lowering via Bempedoic acid, an ACL-Inhibiting Regimen )

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On the contrary, Aslan et al

These nuances underscore the need for more targeted trials in vulnerable subgroups (e.g., frail older adults, those with early cognitive decline, or individuals with low baseline vitamin D)

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