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Description

We have previously reported in rats that acute infusion of GLP-1 potently increases skeletal muscle microvascular perfusion in both acute (lipid infusion) and chronic (high fat diet feeding) insulin resistant states

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Newer options like retatrutide add a third receptor (glucagon) to the mix, which may further affect dietary needs and tolerances

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It is also about the habits built during the process

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Clinical trials have demonstrated significant HbA1c reductions with cardiovascular benefits in high-risk patients

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