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Proton-pump inhibitors (e.g., omeprazole, esomeprazole, and lansoprazole), used to treat Zollinger-Ellison syndrome and gastroesophageal reflux disease (GERD), markedly decrease stomach acid secretion required for the release of vitamin B 12 from food but not from supplements

Protein intake of 1.6-2.0 g/kg body weight during a caloric deficit is supported by extensive weight loss research for lean mass preservation (Wycherley et al., 2012)

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For keeping levels up, adults get 1000 mcg of Vitamin B12 every month

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