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The inhibition of endothelial p53 activation facilitates oxygen consumption and mitochondrial biogenesis by inhibiting the inactivation of endothelial nitric oxide synthase

In a report published late last month in the medical journal The BMJ , a group of American and Chinese researchers raise potential safety concerns about GLP-1 drugs, indicating that higher doses of the drugs were linked to increased risks of experiencing symptoms consistent with stomach paralysis, including persistent nausea, vomiting and irregular bowel movements