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Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid

Structural damage and dysfunction in mitochondria lead to ATP deficiency, ROS overproduction and cytochrome c release, potentially resulting in organ failure (88,89)

Through this mechanism, it is positioned within research exploring normalization of stress-hormone rhythms and sleep-endocrine coordination

Bottom line: Glutathione is a versatile molecule that supports sleep by creating a healthier, less stressed internal environment, rather than by drugging the brain into unconsciousness

Figure 1 Whilst much attention was focused on GLP-1 in the 1980s and 90s, following the discovery of its incretin effect in humans (21), little was known about the physiological role of oxyntomodulin in humans at the time (21, 22)