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435 HSPs and inflammasome regulation in autoimmune diseases Inflammasomes are multiprotein complexes that play a central role in innate immunity by regulating the production of pro-inflammatory cytokines, such as interleukin-1 (IL-1) and IL-18

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For 15 min drug treatment, trophozoites (3034 h post invasion) were incubated with 50 M MB, 1 mM diamide, or 50 mM H 2 O 2

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This motif is necessary for DDX5 to interact with XRN2 and repress formation of cellular R-loops, which is essential for transcriptional termination