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Retatrutide, a triple receptor agonist targeting GIP, GLP-1, and glucagon receptors, represents a newer addition to this class

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Participants were randomly assigned to receive retatrutide at varying doses or placebo over 48 weeks

[16] [17] Semaglutide (as Wegovy) is further indicated as an adjunct to a reduced-calorie diet and increased physical activity for weight management, including weight loss and weight maintenance, in adults with obesity (initial BMI 30 kg/m 2 ) or who are overweight (initial BMI 27 kg/m 2 ) and have at least one weight-related comorbidity such as dysglycemia (prediabetes or type 2 diabetes), hypertension, dyslipidemia, or cardiovascular disease

Neither is a stimulant or a traditional diet pill