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AQP4 is one of the key transport channels in the central nervous system, which is abundant in astrocytes foot processes (Bonomini and Rezzani, 2010)

GHRPs act at the ghrelin receptor (GHSR-1a), a separate receptor from GHRHR, producing a distinct and complementary GH-secretory signal

It has recently been shown that GLP-1R neurons in the dorsomedial hypothalamic nucleus regulate pancreatic activity by affecting the dorsal motor nucleus of the vagus, specifically lowering blood glucose levels by increasing insulin release (Huang et al., 2022)

Akt/mTOR (cell growth, metabolism, and muscle maintenance)